Yanxian Peng, PhD

yanxian

Yanxian earned both her Bachelor of Engineering and Ph.D. from NUS, Division of Bioengineering. She has been focusing on the application of macromolecular crowding for collagen deposition (TML 2005) and the development of human bioassembled matrices for human embryonic stem cell cultivation (TML 2011). She is now a research fellow within TML, working on the application of macromolecular crowding for ex vivo expansion of mesenchymal stem cells.

Publications:

  • Chen C, Loe F, Blocki A, Peng Y, Raghunath M. Applying macromolecular crowding to enhance extracellular matrix deposition and its remodeling in vitro for tissue engineering and cell-based therapies. Adv Drug Deliv Rev. 2011 Mar 30 (Epub ahead of print)
      Chen CZ, Peng YX, Wang ZB, Fish PV, Kaar JL, Koepsel RR, Russell AJ, Lareu RR, Raghunath M. The Scar-in-a-Jar: studying potential antifibrotic compounds from the epigenetic to extracellular level in a single well. Br J Pharmacol. 2009 Nov;158(5):1196-209.
    • Lareu RR, Subramhanya KH, Peng Y, Benny P, Chen C, Wang Z, Ragagopalan R, Raghunath M. Collagen matrix deposition is dramatically enhanced in vitro when crowded with charged macromolecules: the biological relevance of the excluded volume effect. FEBS Lett. 2007 Jun 12;581(14):2709-14
    • Lareu RR, Arsianti I, Subramhanya HK, Yanxian P, Raghunath M. In vitro enhancement of collagen matrix formation and crosslinking for applications in tissue engieering: a preliminary study. Tissue Eng. 2007 Feb; 13(2):385-91.
    • Yanxian Peng and Michael Raghunath, Daniel Eberli (Ed.) “Chapter 5, Learning from Nature: Emulating Macromolecular Crowding to Drive Extracellular Matrix Enhancement for the Creation of Connective Tissue In Vitro”, Tissue Engineering, Croatia: IN-TECH, 2010