Our Research

TML’s research is split in four main research areas:

1. Macromolecular crowding and stem cells platform
2. Scar Wars and self-vascularising materials
3. Biological cross-linking: towards a tissue glue
4. Epigenetics and regenerative medicine

Research projects:

• Emulation and control of crowded environments in hydrogels (Jean-Yves Dewavrin)
• Differentiation of peripheral blood-isolated NG2+ progenitors into astrocytes (Jean-Yves Dewavrin)
• Fabrication of electrospun bioactive tissue engineering scaffolds (Priscilla Peh, Natalie Lim)
• Devicing a rapid isolation method for bone marrow derived stem cells (Priscilla Peh)
• Study of mesenchymal stem cell influence and behavior in a skin organotypic culture (Priscilla Peh)
• Macromolecular crowding and mesenchymal stem cells in vitro (Felicia Loe)
• The Role of Macromolecular Crowding in the Differentiation of Human Mesenchymal Stem Cells (Rafi Rashid)
• Epigenetic Reversal of the Myofibroblast Phenotype to Target Peri-Implantation Fibrosis (Ariel Tan)
• Transglutaminase as a tissue glue (Pradeep Panengad)
• Application of macromolecular crowding for ex vivo expansion of mesenchymal stem cells. (Yanxian Peng)
• Effects of macromolecular crowding on mesenchymal and epithelial cells (Paula Benny)
• Induction of Angiogenesis by using Prolyl Hydroxylase Inhibitors in Microfluidic Devices (Sei Hien Lim)
• Studying adipogenic differentiation using hbmMSCs under crowded environments a novel cell culture platform (Michelle Lee)
• Pharmacologic Stimulation of Angiogenesis and Inhibition of Fibrosis in Tissue-Engineered Constructs (Adeline Sham)
• Bone Tissue Engineering (Clarice Chen)
• Self-vascularizing and antifibrotic materials (Clarice Chen)
• Fibrosis : The Scar-in-Jar (Clarice Chen)